| Frank OzFrank Oz | => | Director / Writer / Fozzie / Cookie Monster / Animal / Bert / Sam the Eagle (voice) / Miss Piggy / Ocean Breeze Soap Board Member |
 |
| Jay TarsesJay Tarses | => | Writer |
| Tom PatchettTom Patchett | => | Writer |
| Ralph BurnsRalph Burns | => | Composer |
| Art CarneyArt Carney | => | Bernard Crawford |
 |
| Brian HensonBrian Henson | => | Additional Muppet Performer (voice) (uncredited) |
 |
| Brian MuehlBrian Muehl | => | Bear / Dog (voice) / Tatooey - Rat |
| Brooke ShieldsBrooke Shields | => | Customer in Pete's |
 |
| Bruce Edward HallBruce Edward Hall | => | Masterson - Rat / Beth Bear (voice) |
| Cyril JenkinsCyril Jenkins | => | The Minister (as Dr. Cyril Jenkins) |
| Dabney ColemanDabney Coleman | => | Martin Price |
 |
| Dave GoelzDave Goelz | => | Chester - Rat / Dog / Gonzo / Beauregard / Zoot / Penguin (voice) / Bill - Frog / Dr. Bunsen Honeydew |
 |
| Elliott GouldElliott Gould | => | Cop in Pete's |
 |
| Gates McFaddenGates McFadden | => | Mr. Price's secretary (as Cheryl McFadden) |
 |
| Gregory HinesGregory Hines | => | Roller skater |
 |
| Jerry NelsonJerry Nelson | => | Lew Zealand / Crazy Harry / Penguin / Chicken / Granny / Bear / Dr. Strangepork / The Count (voice) / Camilla / Floyd / Dog / Pops |
 |
| Jim HensonJim Henson | => | Dr. Teeth / Granny / Rowlf / Ernie / The Newsman (voice) / Kermit the Frog / Swedish Chef / Horse & Carriage Rider / Waldorf / Link Hogthrob |
 |
| Joan RiversJoan Rivers | => | Perfume saleswoman |
 |
| John LandisJohn Landis | => | Leonard Winesop |
 |
| Juliana DonaldJuliana Donald | => | Jenny |
 |
| Karen PrellKaren Prell | => | Yolanda - Rat (voice) |
 |
| Kathryn MullenKathryn Mullen | => | Jill - Frog / Chicken (voice) |
 |
| Linda LavinLinda Lavin | => | Kermit's doctor |
| Liza MinnelliLiza Minnelli | => | Herself |
 |
| Lonny PriceLonny Price | => | Ronnie |
| Louis ZorichLouis Zorich | => | Pete |
 |
| Martin P. RobinsonMartin P. Robinson | => | Additional Muppet Performer / College Student in Audience / Bear (voice) |
| Richard HuntRichard Hunt | => | Janice / Dog (voice) / Statler / Scooter / Beaker |
 |
| Steve WhitmireSteve Whitmire | => | Gill - Frog / Dog / Rizzo the Rat / College Student in Audience / Chicken / Baby Kermit / Lew Zealand (voice) |
 |
