| Episode List: |
| Episode Name | Disc | Disc Order | Directors | Writers | Synopsis | Reaction | IMDB | Personal Rating | Diagnosis | Clinics | Medical Mystery | Solution | Overall Medicine | Soap Opera |
| Dying Changes Everything | 1 | 1 | Deran Sarafian | | A female assistant to a demanding boss collapses in a meeting. Meanwhile, House is preoccupied with Wilson. | A good enough episode. | 8.5 | 8 | ectopic pregnancy and lepromatous leprosy (pretty leprousy) | | B | B | C- | B+ |
| Not Cancer | 1 | 2 | David Straiton | | Several people all suddenly die and the only things they had in common was that they shared an organ donor. | This was a quite intriguing puzzle. | 8.4 | 7 | cancer stem cells | | A | C- | D | C |
| Adverse Effects | 1 | 3 | Andrew Bernstein | | A strugling artist is sent to the hospital after majorly botching a commissioned portrait. | A bit bizzarre but I guess the nature of the final solution allows them a lot of latitude to make up symptoms. | 8.7 | 7 | bezoar / multiple experimental drug testing | | B- | C- | D+ | C+ |
| Birthmarks | 1 | 4 | David Platt | | While House is reluctantly on his way to his father's funeral, his team works the case of a young woman who had a violent episode while in China, looking for her birth parents. | Intriguing idea and the House/Wilson storyline is fun. | 9.2 | 9 | nails in the brain | | B | B | B- | A |
| Lucky Thirteen | 1 | 5 | Greg Yaitanes | | A one night stand for Thirteen collapses and she has to be rushed to Princeton Plainsboro. | We finally gain a fair amount of insight into the very secretive Thirteen in this episode. | 9.0 | 8 | Sjogren's Syndrome | | C- | C- | D | B+ |
| Joy | 2 | 1 | Deran Sarafian | | Cuddy's baby mama appears to have something wrong with her while House deals with a man who appears to snort in his sleep. | This one is a bit of a roller coaster for Cuddy. | 8.7 | 7 | Familial Mediterranean Fever // placental abruption | | B+ | D | C | B+ |
| The Itch | 2 | 2 | Greg Yaitanes | | An agoraphobic male needs to be diagnosed and treated within his own home, and House avoids confronting what happened between Cuddy and himself. | Not the funnest episode, but it's interesting to see how House deals with the restriction of diagnosing a man at home. | 8.7 | 7 | lead poisoning | | C+ | A- | B- | A- |
| Emancipation | 2 | 3 | James Hayman | | An emancipated minor collapses at work. | A nice episode that, in an interesting twist, has House practically begging Wilson to stick his nose in and tell him what he thinks. | | 8 | acute promyelocytic leukemia // iron toxicity | | B+ | A- | B- | B- |
| Last Resort | 2 | 4 | Katie Jacobs | | A desperate patient takes House, Thirteen and a handful of patients hostage in order to be diagnosed. | Nice setup for the episode which leads to some fun drama. | 8.7 | 8 | melioidosis | | A- | C | D | B+ |
| Let Them Eat Cake | 2 | 5 | Deran Sarafian | | A fitness guru passes out while filming a commercial for her DVD. | Watchable enough. | 8.8 | 8 | hereditary coproporphyria | | A | B | B | A |
| Episode Name | Disc | Disc Order | Directors | Writers | Synopsis | Reaction | IMDB | Personal Rating | Diagnosis | Clinics | Medical Mystery | Solution | Overall Medicine | Soap Opera |
| Joy to the World | 3 | 1 | David Straiton | | A sixteen year old hallucinates and collapses after falling victim to an on stage prank. | A fairly solid episode. Not particularly deep in the medicine, but the soap opera was quite fun. | 8.8 | 9 | eclampsia | Asthma (perfume inhaler?) / Virgin Birth! | B | A | B | A- |
| Painless | 3 | 2 | Andrew Bernstein | | A man in constant pain attempts to end it through suicide. | Okay episode. Nothing particularly dwaring though. | 8.2 | 6 | epilepsy | | D | D | C- | C |
| Big Baby | 3 | 3 | Deran Sarafian | | A woman who works with special needs kids starts coughing up blood. | An intriguing final diagnosis. The episode, is watchable enough. | 8.3 | 7 | patent ductus arteriosus | | B | B+ | C | B |
| The Greater Good | 3 | 4 | Lesli Linka Glatter | | A doctor who quit to pursue her own happiness collapses in a cooking class. | Fun episode. I like Cuddy's comment that House has dragged her down to his level. | 8.5 | 7 | endometriosis | | B | B | C | B |
| Unfaithful | 3 | 5 | Greg Yaitanes | | A disillusioned, alcoholic priest is admitted to the hospital after "seeing" a stigamtic Christ floating outside his door. | The medicine is haphazard here, but the soap opera is actually pretty good. | 8.6 | 8 | Wiskott-Aldrich Syndrome | | B+ | C- | C- | A- |
| The Softer Side | 4 | 1 | Deran Sarafian | | A teenager, genetically both male and female, collapses with abdominal pains after scoring the winning basket. | The strong point in this one is the soap opera, though the mystery was interesting enough. | 8.7 | 8 | dehydration / contrast complications | Broken Finger | B+ | B | C+ | B |
| The Social Contract | 4 | 2 | Andrew Bernstein | | A man comes down with a case of the "absolutely honest"s. | A bit scary to consider what I migh let slip if I had the same condition. | 8.7 | 8 | Doege-Potter Syndrome / autoimmune | | A | B+ | C | A |
| Here Kitty | 4 | 3 | Juan José Campanella | | A woman comes in claiming a cat predicted she would die. | Not much in this episode to really make it stand out. | 8.3 | 6 | carcinoid tumor in the appendix | | B- | B | C | B- |
| Locked In | 4 | 4 | Daniel Attias | | House takes the case of a man who is unable to communicate with the world outside his head. | This one uses some intriguing story techniques. | 9.1 | 9 | Leptospirosis | | A- | D | C- | C |
| Simple Explanation | 4 | 5 | Greg Yaitanes | | Kutner's suicide comes at a time when Taub is treating a woman whose husband seems to get better as she gets worse. | Quite a surprise and shock.9. | 9.0 | 7 | visceral leishmaniasis | | A- | B | B | A |
| Episode Name | Disc | Disc Order | Directors | Writers | Synopsis | Reaction | IMDB | Personal Rating | Diagnosis | Clinics | Medical Mystery | Solution | Overall Medicine | Soap Opera |
| Saviors | 5 | 1 | Matthew Penn | | An environmentalist collapses after a protest. | An okay episode, not my favorite. The patient can be quite annoying. | 8.5 | 7 | sporotrichosis | | B+ | B- | D | B+ |
| House Divided | 5 | 2 | Greg Yaitanes | | House takes the case of a deaf teen who develops exploding head syndrome. | This is a fine episode and it's interesting to see House go slowly mad. | 9.1 | 8 | sarcoidosis | | B | B | B- | A |
| Under My Skin | 5 | 3 | David Straiton | | An accident at a ballet recital lands a diva in the hospital with her skin falling off. | Not my favorite. Okay. | 9.0 | 8 | gonorrhea | | B- | D | F | B+ |
| Both Sides Now | 5 | 4 | Greg Yaitanes | | A young man with a severed corpus callosum lands himself on House's radar while House decides to try to make Cuddy angry to win her over. | This is an interesting episode and a rather intriguing way to end the season. | 9.5 | 9 | bad deodorant | | C | B | B | A |
