Jodie FosterJodie Foster was initially offered the role of Alice.
Jerry's cab is numbered 1S48. The bus that Jerry hooks up to the fruit cart is 1648. This is a tribute to stuntman [?] Harry Wowchuk who worked on this movie and who was born on October 16, 1948 and who has worked with Richard DonnerRichard Donner and Joel SilverJoel Silver on three movies.
The character names "Dr. Jonas" (Patrick StewartPatrick Stewart), and "Agent Lowry" (Cylk CozartCylk Cozart), were both named after British character actor Morton Lowry, who portrayed the school teacher Mr. Jonas in How Green Was My Valley.
The doctor who lets Julia RobertsJulia Roberts into the restricted area to see Mel GibsonMel Gibson handcuffed to the bed is Gibson's younger brother Donal GibsonDonal Gibson.
When Jerry is in the hospital for the first time (where he writes the word Geronimo on the wall), the room number on the hospital door is briefly visible: 322. This number is well-known in conspiracy circles as being the address of the Skull & Bones society at Yale University, which is said to have the skull of Geronimo in its possession.
Director Cameo: [Richard DonnerRichard Donner] Jerry's cab passenger in the opening credits.
In the movie several times an earthquake is referenced that took place in southern coast with a magnitude of 7.3 during a presidential visit. There indeed happened a 7.3 earthquake in North-West part of Turkey in 1999, just to be followed by a presidential visit.
According to director Richard DonnerRichard Donner, Mel GibsonMel Gibson improvised the opening scenes in which his character expounds his conspiracy theories to a succession of passengers.
Jerry runs into a theatre showing Ladyhawke, also directed by Richard DonnerRichard Donner.