Random Trivia For This Title:
- Ryan Reynolds' full body makeup took eight hours to apply. Once it was on, he was not able to sit or lie down.
- The serum Wade is injected with can be seen to have drops of blood in it, a reference to Deadpool's healing factor stemming from Wolverine's. In the original comic books, Deadpool garnered his healing factor from an experiment involving a sample of Wolverine's blood. This allowed him to survive further experimentation, but cannot heal any prior scarring, nor the cancer afflicting him (It progresses as fast as he can heal).
- During a talk at Google, Ryan Reynolds revealed that the taxi driver character "Dopinder" was named after "a really cool guy" he knew in elementary school, who died when he was hit by lightning. It was meant to be a tribute to him.
- Ryan Reynolds was allowed to keep his Deadpool costume after filming had completed (he didn't ask to, nor did he give anyone the chance to take it from him). He has said that Deadpool will be the last comic book character he will ever portray. However, he is open to Deadpool sequels and/or cameos.
- The Deadpool costume originally had a muscle layer underneath but it had to be removed: Ryan Reynolds was so muscular, the costume was not only too tight for him, but it made him look overlarge.
- In the trailer and in the film, Wade Wilson requests, "Don't make the super suit green--or animated!" This is a reference to Ryan Reynolds' previous role as the DC superhero Green Lantern, in which, as stated, the green suit was a special effect rather than an actual costume for Reynolds to put on. This is also a crude reference to that film's director, Martin Campbell, who he did not get along with. He pokes even more fun at the costume in a deleted scene on the Blu-Ray copy of the movie.
- This film had a lower budget than any of the [X-Men], [Iron Man], [Avengers], or [Captain America] movies.
- In the comics, Negasonic Teenage Warhead is actually a telepath and precognitive mutant. Her abilities were changed for the film due to the fact that the writers felt that by having explosive powers, it would fit more with her name.
- Ryan Reynolds describes Deadpool's "breaking the fourth wall" ability as a reflection of current times, "I think Deadpool's coming along at the right time, because it's speaking to that generation that has seen all these comic-book films and enjoyed them all; it's speaking to them as though the guy in that red suit is one of them. It's like watching a DVD commentary by someone who's got some pop-culture savvy and is kind of funny and a little obnoxious and is saying the things that you wouldn't say."
- When Gina Carano did the junkyard fight scene, she was more worried about spiders than anything else, even her stunts.
- Throughout the film, Deadpool accuses the studio of not having enough money to pay for several elements in the movie. In fact, Fox Studios cut seven million dollars out of the film's budget at the last minute, necessitating several rewrites. Items cut from the film included a motorcycle chase between Wade and Francis, the addition of more named villains, and several action sequences. In the latter instance, the fights were scaled down by having Deadpool forget to bring his ammo and gun bags.
- Towards the end when Deadpool is fighting the soldiers, he stops for a moment when he recognizes one of them as "Bob". Bob, agent of HYDRA, is a recurring character in Deadpool comic books, who is a cowardly sidekick type character and is often reluctantly forced to aid Deadpool in his escapades. The HYDRA aspect of the character was removed for obvious licensing reasons.
- Greg LaSalle, who did face capture work of Colossus, found it difficult to perform the character vomiting after Ajax gets his head shot. LaSelle had to hyperventilate, as well as tense his body, to get his face to react.
- During the final fight scene, the carrier that Ajax and Deapool are fighting on is actually a destroyed Helicarrier from Captain America: The Winter Soldier.